Cushing's disease is a rare condition characterized by the overproduction of cortisol, a hormone that helps regulate metabolism and stress response. It is caused by a benign tumor on the pituitary gland that stimulates the production of cortisol. Symptoms of Cushing's disease include weight gain, high blood pressure, fatigue, muscle weakness, and mood changes. Treatment typically involves surgical removal of the tumor, medication to suppress cortisol production, or radiation therapy. Research in this area focuses on understanding the underlying causes of Cushing's disease, improving diagnostic methods, and developing more effective treatments.